Pharmacological action Minocycline 100 mg
Antibiotic tetracycline. Bacteriostatic effect by inhibiting protein synthesis by reversibly binding to ribosomal 30S subunit of susceptible microorganisms.
It is active against gram-positive bacteria: Staphyloccocus aureus, Streptococcus spp., Nocardia spp., Listeria spp., Bacillus anthracis; Gram-negative bacteria: Neisseria meningitidis, Bartonella bacilliformis, Vibrio cholerae, Esherichia coli, Klebsiella spp., Shigella spp., Acinetobacter spp. , Haemophilus spp.; anaerobic bacteria: Clostridium spp., Bacteroides spp.
Minocycline is also active against Mycobacterium spp. (Including Mycobacterium leprae), Chlamydia spp., Ureaplasma urealyticum, Treponema pallidum.
Statement Minocycline 100 mg
Acne, nocardiosis, leprosy (in combination therapy), infectious and inflammatory diseases caused by pathogens susceptible to minocycline (including pneumonia, bronchitis, empyema, tonsillitis, cholecystitis, pyelonephritis, intestinal infections, endocarditis, endometritis, prostatitis , syphilis, gonorrhea, brucellosis, rickettsioses, purulent soft tissue infection, osteomyelitis, and trachoma).
Dosage regimen Minocycline 100 mg
When administered daily dose for adults is 100-200 mg.
For children older than 8 years the dose is 4 mg / kg followed by 2 mg / kg every 12 hours
Side effect Minocycline 100 mg
Perhaps: vestibular disorders (dizziness, unsteadiness), pigmentation of the skin and mucous membranes, Hepatotoxic effects, nausea, vomiting, candidiasis.
Contraindications Minocycline 100 mg
Abnormal liver function, children under 8 years old, increased sensitivity to tetracycline.
Pregnancy and breastfeeding Minocycline 100 mg
Minocycline crosses the placental barrier and is excreted in breast milk.
Do not apply during the second half of pregnancy and lactation, as Minocycline causes tooth discoloration, enamel hypoplasia and dysplasia of bones of the fetus and child.
Cautions
When taken with milk and milk products is disturbed absorption of minocycline.
Minocycline causes tooth discoloration, enamel hypoplasia and dysplasia of bones of the fetus and child, so do not use minocycline in children younger than 8 years.
